The cost-effectiveness of predictive algorithm guided primary antidepressant treatment: economic evaluation of the multinational PReDicT randomised controlled trial

Key Points

• This research aims to evaluate the cost-effectiveness of predictive algorithms in guiding antidepressant treatment.
• Economic evaluation accompanying the PReDicT randomized controlled trial.
• Comparison of treatment and control arms regarding health outcomes and costs.
• Analysis of country-level variations in cost-effectiveness.
• Potential health benefits observed from closely monitored antidepressant treatment.
• Improved capabilities noted with predictive algorithm use, though with uncertainty in benefits.
• Country-level variations indicated significant uncertainty in cost-effectiveness outcomes.

Abstract