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Peptoid-based antimicrobial strategies against polymyxin-resistant Gram-negative bacteria | Synapse

April 15, 2026Open Access

Peptoid-based antimicrobial strategies against polymyxin-resistant Gram-negative bacteria

Key Points

The aim is to evaluate TM8 as a potential antimicrobial candidate targeting polymyxin-resistant bacteria.
Evaluation of antimicrobial efficacy of TM8 against polymyxin-resistant bacteria.
Recommendations for further studies on safety and pharmacokinetics of TM8.
TM8 shows promise as an antimicrobial agent against resistant strains.
Further studies are needed to assess safety profiles and detailed pharmacological properties.

Abstract

This study presents TM8 as a potential candidate antimicrobial against polymyxin-resistant bacteria. Further studies are recommended focusing on safety, pharmacokinetics and pharmacodynamics of this compound.

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Cite this study

Mishra et al. (Wed,) studied this question.

www.synapsesocial.com/papers/69df2b85e4eeef8a2a6b0880 — DOI: https://doi.org/10.1093/jambio/lxag093

Authors

S

Shyam Kumar Mishra

J

Jiawei Shen

T

Tanzina Akter

Journals

Journal of Applied Microbiology

Actions

Institutions

Stanford University

The University of Sydney

UNSW Sydney

References and Citations

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