A Novel Therapy for Keloid Following Toe Syndactyly Division in Children: 1470 nm Laser and Glucocorticoid Injection (1470 LAGI)

Background Keloid development following toe syndactyly division is a rare but troublesome condition, which can impose both esthetic and functional burden. Currently, there is no effective treatment for this condition. The present study proposed a new treatment for keloid after syndactyly division by 1470 nm laser and glucocorticoid injection (1470 LAGI). This study aimed to evaluate the efficacy of this treatment modality. Methods A retrospective study was conducted on 12 patients with 36 keloid cases, who underwent treatment with 1470 LAGI. VSS scores were applied for keloid evaluation (pigmentation, vascularity, pliability, and height). VAS was applied for assessing pain and itching, and the recovery rate was recorded. Results This study showed that the 1470 LAGI can improve the pathological status of keloids from toe syndactyly division ( p < 0.001), with a recovery rate of 30.56%. Itching and pain also significantly improved ( p < 0.001). Conclusion In terms of vascularity, pigmentation, pliability, and height, 1470 LAGI led to keloid regression after toe syndactyly division, with a recovery rate of 30.56%. Besides, the combined treatment significantly decreased the episodes of itching and pain, thereby improving the quality of life. Therefore, it is an effective minimally invasive treatment for keloid following toe syndactyly division in children.