Local Control Outcomes of Patients With Brain Metastases From Small Cell Lung Cancer Treated With Stereotactic Radiosurgery

Key Points

• This research aims to evaluate the effectiveness of stereotactic radiosurgery (SRS) on local control outcomes in patients with brain metastases from small cell lung cancer.
• Analyzed local control (LC) outcomes in patients treated with SRS for brain metastases.
• Considered prior treatments like prophylactic cranial irradiation (PCI) and whole-brain radiotherapy (WBRT).
• Recommended prescription dose ≥20 Gy or staged SRS when applicable.
• SRS demonstrated high local control rates for small cell lung cancer brain metastases.
• Overall survival (OS) was limited due to systemic disease progression.
• The study indicates that higher doses or staged SRS may enhance treatment outcomes.

Abstract