To Give or Not to Give: Thrombolysis for Massive Pulmonary Embolism in a Patient with Profound Anaemia

Key Result

Systemic thrombolysis with 100 mg recombinant tPA was successfully and safely administered to a patient with massive pulmonary embolism and profound anaemia (haemoglobin 4.5 g/dL).

Key Points

• This research aims to assess the use of thrombolysis in patients with massive pulmonary embolism and profound anaemia.
• Patient evaluation on arrival included vital signs and physical examination.
• Assessment of symptoms such as pallor and jaundice.
• No signs of active bleeding were noted during the examination.
• Initial vital signs indicated hypotension with a blood pressure of 90/50 mmHg.
• Oxygen saturation was critically low at 83% on room air.
• Cardiopulmonary examination was largely unremarkable.