Prognostic interaction between clinical stage and left atrial remodeling in dogs with myxomatous mitral valve disease

Key Points

• The aim is to evaluate how left atrial remodeling interacts with clinical stage to influence prognosis in dogs with myxomatous mitral valve disease.
• Evaluated dogs diagnosed with myxomatous mitral valve disease
• Measured left atrial (LA) size to assess remodeling
• Analyzed survival outcomes based on clinical stage and LA size
• Severe LA enlargement in preclinical disease worsens prognosis, similar to CHF with mild-to-moderate LA enlargement
• Prognosis cannot be determined by clinical stage alone; LA remodeling impacts outcomes significantly