Foetal-onset biventricular noncompaction with an MYH7 variant transitioned from prenatal right heart failure to progressive left heart failure at 5 months of age.
Case Report (n=1)
No
Postnatal hemodynamic changes can influence the biventricular noncompaction phenotype in MYH7 variants, leading to a transition from fetal right heart failure to postnatal left heart failure.
Abstract We report a case of foetal-onset biventricular noncompaction with an MYH7 variant. Prenatal fetal hydrops and right heart failure resolved after birth, but progressive left heart failure developed at 5 months. This transition reflects how postnatal hemodynamic changes influence the biventricular noncompaction phenotype, necessitating vigilant monitoring for left heart failure in foetal-onset biventricular noncompaction cases with MYH7 variants.
Yamada et al. (Wed,) conducted a case report in Biventricular noncompaction with an MYH7 variant (n=1). Foetal-onset biventricular noncompaction with an MYH7 variant transitioned from prenatal right heart failure to progressive left heart failure at 5 months of age.