Introduction: cytotoxic effects of three calcium silicate-based cements Mineral Trioxide Aggregate (MTA), Biodentine, and Calcium Enriched Mixture (CEM) Cement, focusing on their biocompatibility with human dental pulp cells in vital pulp therapy (VPT). Materials and Methods: ., MTT) were included. Results: <0.05). No other concentrations or exposure durations showed significant cytotoxic effects. CEM cement consistently demonstrated favorable biocompatibility across the included studies. Conclusion: biocompatibility for vital pulp therapy. Their biological responses may be influenced by material concentration and exposure duration, emphasizing the importance of careful and controlled clinical application.
choleh et al. (Thu,) studied this question.