Compared with White patients, Black and Hispanic patients (comprising 12.9% of 469,175 TAVR hospitalizations) had higher adjusted odds of major adverse cardiovascular events.
Observational (n=469,175)
Yes
Do Black and Hispanic patients have worse in-hospital outcomes compared to White patients following TAVR in urban hospitals?
There are persistent racial and ethnic disparities in in-hospital outcomes following TAVR in urban hospitals, with Black and Hispanic patients experiencing higher rates of MACE and Hispanic patients facing higher mortality compared to White patients.
INTRODUCTION: Transcatheter aortic valve replacement (TAVR) is an established treatment for severe aortic stenosis. Although TAVR has improved clinical outcomes, data on racial and ethnic differences in in-hospital clinical outcomes and their temporal trends, particularly within urban hospital settings, remain limited. Accordingly, we examined racial and ethnic differences in in-hospital outcomes and their temporal trends among patients undergoing TAVR in urban hospitals. METHODS: We utilized the National Inpatient Sample from 2016 through 2022 and identified TAVR-related hospitalizations in urban hospitals. Patients were classified by race and ethnicity, with White patients serving as the reference group. Primary endpoints included in-hospital mortality and major adverse cardiovascular events. Secondary endpoints included acute myocardial infarction, stroke, cardiac arrest, acute kidney injury, need for transfusion, mechanical ventilation, and other in-hospital complications. Survey-weighted multivariable analyses were performed. RESULTS: We identified a weighted total of 469,175 hospitalizations for TAVR in urban hospitals. Overall, 87.1% of patients were White, and 12.9% were racial and ethnic minority patients. Compared with White patients, Black and Hispanic patients had higher adjusted odds of major adverse cardiovascular events, driven in part by acute myocardial infarction, while Hispanic patients also had higher in-hospital mortality. Rates of ischemic and hemorrhagic stroke did not differ significantly across groups. Significant race-by-year interactions were observed for in-hospital mortality and blood transfusion. CONCLUSIONS: Our findings highlight persistent racial and ethnic disparities in in-hospital outcomes following TAVR, emphasizing the need for targeted efforts to address inequities in care delivery.
Munshi et al. (Wed,) conducted a observational in Severe aortic stenosis (n=469,175). Racial and ethnic minority status (Black and Hispanic) vs. White patients was evaluated on In-hospital mortality and major adverse cardiovascular events. Compared with White patients, Black and Hispanic patients (comprising 12.9% of 469,175 TAVR hospitalizations) had higher adjusted odds of major adverse cardiovascular events.