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Multi-platform mutational, proteomic, and metabolomic spatial mapping was used on the whole-organ scale to identify the molecular evolution of bladder cancer from mucosal field effects. We identified complex proteomic and metabolomic dysregulations in microscopically normal areas of bladder mucosa adjacent to dysplasia and carcinoma
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Bogdan Czerniak
Sangkyou Lee
Sung Yun Jung
Johns Hopkins University
Columbia University
The University of Texas MD Anderson Cancer Center
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Czerniak et al. (Wed,) studied this question.
www.synapsesocial.com/papers/68e6fa98b6db643587674fd7 — DOI: https://doi.org/10.21203/rs.3.rs-3994376/v1