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In terms of hematologic and cytogenetic responses, tolerability, and the likelihood of progression to accelerated-phase or blast-crisis CML, imatinib was superior to interferon alfa plus low-dose cytarabine as first-line therapy in newly diagnosed chronic-phase CML.
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Stephen G. O’Brien
François Guilhot
Richard A. Larson
New England Journal of Medicine
University of Chicago
Heidelberg University
The University of Texas MD Anderson Cancer Center
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O’Brien et al. (Thu,) studied this question.
www.synapsesocial.com/papers/6985f297db3aef8684169ecd — DOI: https://doi.org/10.1056/nejmoa022457
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