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In silico assessment of cyanobacterial alkaloids as probable medications against SARS-CoV-2 | Synapse
March 3, 2026
Open Access
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In silico assessment of cyanobacterial alkaloids as probable medications against SARS-CoV-2
AS
Animesh Sen
HC
Hemantha Mani Kumar Chakravarthi Chanda
Sri Venkateswara Institute of Medical Sciences
SC
Srinivasulu Cheemanapalli
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Key Points
Cyanobacterial alkaloids show potential bioactivity against SARS-CoV-2, indicating possible therapeutic applications.
Molecular docking studies provided significant insights, with top candidates demonstrating high affinity, such as 9.3 kcal/mol.
Assessing the bioactivity using in silico methods allowed for a systematic evaluation of potential interventions.
Further validation in clinical settings is needed to confirm efficacy and safety in human populations.
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Sen et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75b76c6e9836116a22ca6
https://doi.org/https://doi.org/10.1016/j.insi.2026.100215