Comparison of Laser Doppler Flowmetry With Contrast‐Enhanced Ultrasound to Approximate Placental Microvascular Blood Flow in the African Green Monkey ( Chlorocebus aethiops sabaeus )

Key Points

• Discordant results were observed between laser doppler flowmetry and contrast-enhanced ultrasound regarding placental perfusion.
• Specifically, laser doppler flowmetry proved unsuitable for measuring microvascular blood flow in a heterogeneous organ like the placenta.
• This assessment involved using advanced imaging techniques to study blood flow in the placenta of African green monkeys over a defined period.
• The findings highlight potential limitations of using LDF in complex biological structures, indicating a need for better methodologies.