Repurposing ramipril to mitigate EMT-like transition in endometriosis by PI3K/AKT/S6K1 signalling pathway: a study in endometriosis induced rats

Key Points

• Ramipril effectively mitigates EMT-like transition in endometriosis-induced rats, highlighting its potential therapeutic role.
• In the analysis, a notable decrease in EMT markers was observed following ramipril treatment within 14 days.
• The study employed endometriosis-induced rat models to evaluate the effects of ramipril on PI3K/AKT/S6K1 signalling.
• These findings support the repurposing of ramipril, though further exploration is needed in clinical settings.