March 3, 2026

Does Hormone Replacement Therapy Influence Melasma Development? A Review of the Evidence and Management Guidelines

Key Points

Melasma risk is increased in women receiving hormone replacement therapy, and more studies are needed.
A strong emphasis should be placed on photoprotection measures for women at risk of developing melasma.
Prospective studies aim to clarify the relationship between various hormone replacement therapy formulations and melasma.
Counseling at-risk women is crucial for preventing the onset of melasma and enhancing treatment outcomes.

Abstract

HRT-associated melasma is underrepresented in the literature. Clinicians should counsel at-risk women on melasma risk and ensure strict photoprotection. Prospective studies are needed to clarify melasma risk across different HRT formulations.

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Cite This Study

Abdeen et al. (Wed,) studied this question.

synapsesocial.com/papers/69a75d3bc6e9836116a26ed3 https://doi.org/https://doi.org/10.1097/dss.0000000000005032

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