GC-MS profiling, anticancer activity of Moringa oleifera Lam. hydroalcoholic fruit extract against colorectal cancer cells, and In Silico targeting of BRAF in the serrated pathway

Key Points

• Moringa oleifera extract demonstrated significant anticancer activity against colorectal cancer cells, indicating its potential for treatment.
• In silico targeting revealed promising interactions with BRAF within the serrated pathway, providing insights into molecular mechanisms.
• Assessment using GC-MS profiling highlighted the composition of the hydroalcoholic extract, correlating specific compounds with anticancer effects.
• Further exploration on human models needed to validate the observed effects of the Moringa oleifera extract on cancer cells.