Different involvement pattern of striatal subregions in relation to REM sleep behavior disorder in Parkinson's disease

Key Points

• REM sleep behavior disorder is linked to specific striatal subregions in Parkinson's disease patients, highlighting its complexity.
• Striatal subregions exhibit different patterns of involvement, with dopaminergic pathways playing a crucial role.
• Analysis across multiple Parkinson's disease cohorts helps clarify the relationship between neuroanatomy and sleep disorders.
• Understanding these patterns may lead to new treatment strategies for managing REM sleep behavior disorder.