Is selenate a diabetogenic form of selenium? Evidence from a natural experiment in Northern Italy

Key Points

• Selenate appears to increase diabetes risk through oxidative stress mechanisms, impacting glucose metabolism.
• Patients exposed to higher selenate levels show a statistically significant increase in diabetes incidence over time.
• Observational analysis across Northern Italy identifies patterns linking selenate exposure and diabetes outcomes.
• Findings support further exploration into selenium's role in metabolic disorders and diabetes prevention strategies.