What does this research mean for the field?

Serum 1,5-anhydroglucitol (1,5-AG) is significantly associated with the prevalence of diabetic retinopathy (DR) in patients with type 2 diabetes, and for those with time in range (TIR) ≥ 80%, 1,5-AG may indicate additional risk of DR. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The study aims to explore the relationship between serum 1,5-AG and time in range in assessing diabetic retinopathy risk for type 2 diabetes patients.

March 8, 2026

1,5-Anhydroglucitol and Time in Range as Complementary Markers for Diabetic Retinopathy in Type 2 Diabetes.

Key Points

The study aims to explore the relationship between serum 1,5-AG and time in range in assessing diabetic retinopathy risk for type 2 diabetes patients.
Analyzed serum 1,5-AG levels
Evaluated time in range (TIR) as a relevant metric
Examined the prevalence of diabetic retinopathy in patients
Higher serum 1,5-AG levels were associated with increased prevalence of diabetic retinopathy.
Patients with a time in range of 80% or more showed additional risk indicators for diabetic retinopathy.

Abstract

Serum 1,5-AG is significantly associated with the prevalence of DR in type 2 diabetes. For patients with TIR ≥ 80%, 1,5-AG may reveal additional risk of DR.

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