What question did this study set out to answer?

To evaluate the relationship between fibrinogen to albumin ratio (FAR) and sepsis-associated acute kidney injury (SA-AKI).

March 8, 2026Open Access

Association of fibrinogen to albumin ratio with sepsis-associated acute kidney injury: A retrospective cohort study based on the MIMIC-IV database

Key Points

To evaluate the relationship between fibrinogen to albumin ratio (FAR) and sepsis-associated acute kidney injury (SA-AKI).
Retrospective cohort study using MIMIC-IV database
Inclusion of patients without COPD and hypertension
Assessment of FAR levels in relation to SA-AKI incidence
Statistical analysis of outcomes based on timing of SA-AKI occurrence
Elevated FAR levels correlated with higher incidence of SA-AKI
Statistical significance noted only when SA-AKI occurred post-ICU day 3
Further research warranted to explore this association further

Abstract

An elevated FAR level was associated with an increased incidence of SA-AKI in patients without COPD and hypertension. However, this association reached statistical significance only when SA-AKI occurred after ICU day 3. Further research is needed to investigate this association.

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