Clotrimazole‐loaded PLGA microparticles for local drug delivery to the vagina: Shape does matter

Key Points

• The aim is to explore the effectiveness of clotrimazole-loaded PLGA microparticles for vaginal drug delivery.
• Developed clotrimazole-loaded PLGA microparticles for local delivery.
• Investigated the impact of microparticle shape on drug release rates.
• Analyzed the efficacy of the formulation against VVC and other health issues.
• Microparticle shape was found to significantly influence drug release rates.
• The formulated system shows promise for managing vaginal health conditions.