What question did this study set out to answer?

To identify protein signatures that serve as biomarkers for predicting the risk of cardiometabolic diseases in individuals with preserved ratio impaired spirometry (PRISm).

April 10, 2026Open Access

Plasma proteomic signatures linking preserved ratio impaired spirometry to cardiometabolic diseases and multimorbidity: A longitudinal cohort study

Key Points

To identify protein signatures that serve as biomarkers for predicting the risk of cardiometabolic diseases in individuals with preserved ratio impaired spirometry (PRISm).
Conducted a longitudinal cohort study
Analyzed plasma proteomic signatures
Focused on individuals with PRISm
Assessed the relationship between biomarkers and cardiometabolic complications
Identified specific protein signatures linked to PRISm
Demonstrated potential for early identification of high-risk individuals
Indicated that these biomarkers could inform preventive strategies for cardiometabolic diseases

Abstract

The identified protein signatures offer promising biomarkers for risk prediction, enabling early identification of high-risk individuals with PRISm and informing targeted preventive strategies for cardiometabolic complications.

Plasma proteomic signatures linking preserved ratio impaired spirometry to cardiometabolic diseases and multimorbidity: A longitudinal cohort study

Key Points

Abstract

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