What question did this study set out to answer?

To explore the connection between PTPN22 and NLRP3 gene polymorphisms and the risk of developing psoriasis.

April 10, 2026

Association of PTPN22 and NLRP3 Gene Polymorphisms with Psoriasis Susceptibility in a Han Chinese Population

To explore the connection between PTPN22 and NLRP3 gene polymorphisms and the risk of developing psoriasis.
Genetic analysis of the PTPN22 rs2488457 locus
Examination of allele distribution in the Jiujiang population
Comparison of genotypes among individuals with psoriasis and healthy controls
The GG genotype and G allele of PTPN22 rs2488457 may increase susceptibility to psoriasis
Statistical significance was observed in the association between the GG genotype and psoriasis risk.

In the Jiujiang population, the GG genotype and G allele of the PTPN22 rs2488457 locus may be key factors influencing psoriasis susceptibility.

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