Functionally Graded Bilayer Polyurethane Sponge with Sequential Stage-Adaptive Capabilities for Full-Cycle Repair of Infected Wounds

Key Points

• The aim is to develop a multifunctional dressing for effective management of infected, full-thickness wounds.
• Developed a bilayer polyurethane sponge with adaptive capabilities.
• Monitored healing functions across different stages of wound recovery.
• Evaluated the sponge's performance in infected wound models.
• The bilayer sponge successfully facilitated coordinated healing stages.
• Demonstrated enhanced wound closure and infection management.
• Showed significant improvements compared to standard treatments.