Multifunctional ginsenoside Rg3-integrated liposomes for synergistic chemo-photothermal-immunotherapy against multidrug-resistant breast cancer

Key Points

• This work aims to develop a multifunctional liposome that addresses multidrug resistance in breast cancer.
• Developed liposomes by replacing cholesterol with ginsenoside Rg3.
• Incorporated DSPE-PEG2000 for extended circulation time.
• Encapsulated therapeutic agents for combined treatment approaches.
• Enhanced therapeutic efficacy in overcoming multidrug resistance.
• Improved systemic circulation and targeting of cancer cells.
• Synergistic effects observed in chemo-photothermal-immunotherapy.

Abstract