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Le trametinib, comparé à la chimiothérapie, a amélioré les taux de survie sans progression et la survie globale chez des patients atteints de mélanome métastatique avec une mutation BRAF V600E ou V600K. (Financé par GlaxoSmithKline; METRIC ClinicalTrials.gov numéro, NCT01245062.).
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Keith T. Flaherty
Caroline Robert
Peter Hersey
New England Journal of Medicine
Massachusetts General Hospital
Inserm
Heidelberg University
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Flaherty et al. (jeu,) ont étudié cette question.
www.synapsesocial.com/papers/69d97f6ac7f0c3ae80a3dbb9 — DOI: https://doi.org/10.1056/nejmoa1203421
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