What question did this study set out to answer?

This research aims to investigate how resveratrol can reduce renal injury caused by ischemia and reperfusion in diabetic conditions.

April 12, 2026Open Access

Resveratrol inhibits renal ischemia and reperfusion injury in diabetes via reducing oxidative stress, inflammation, and apoptosis

Key Points

This research aims to investigate how resveratrol can reduce renal injury caused by ischemia and reperfusion in diabetic conditions.
Evaluated the effects of resveratrol in a diabetic model of renal ischemia/reperfusion injury
Assessed oxidative stress levels and inflammatory markers
Analyzed signaling pathways including Nrf2/HO-1 and TLR4/NF-κB
Resveratrol significantly reduced signs of kidney injury during ischemia/reperfusion
It lowered oxidative stress and inflammatory responses
The study highlighted enhanced Nrf2/HO-1 signaling and reduced TLR4/NF-κB activity.

Abstract

These findings indicate that RSV could attenuate renal I/R injury in diabetes, possibly by enhancing Nrf2/HO-1 signaling and suppressing the TLR4/NF-κB pathway.

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Authors

Daojing Gong

Xiaobo Chen

Ziqiang Dong

Journals

Renal Failure

Actions

Institutions

China Three Gorges University

Yichang Central People's Hospital

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Resveratrol inhibits renal ischemia and reperfusion injury in diabetes via reducing oxidative stress, inflammation, and apoptosis

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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