Fatal Donor-Derived Disseminated Acanthamoeba Infection in a Liver Transplant Recipient

Key Points

• This study examines the fatal effects of Acanthamoeba infection in a liver transplant recipient.
• Case report of a liver transplant recipient who developed encephalitis.
• Post-mortem analysis of organs revealed Acanthamoeba presence.
• Indirect immunofluorescence assay was used to confirm the infection in donor brain tissue.
• The recipient died from rapidly progressive encephalitis caused by Acanthamoeba.
• Acanthamoeba was detected in multiple organs, including the transplanted liver.
• The donor history included kidney transplantation and previous encephalitis, highlighting potential donor risks.

Abstract