Neutrophil-to-lymphocyte ratio mediates pulmonary consolidation through oxidative stress in children with Mycoplasma pneumoniae pneumonia

Key Points

• This research aims to investigate how the neutrophil-to-lymphocyte ratio affects pulmonary consolidation in children with Mycoplasma pneumoniae pneumonia through oxidative stress mechanisms.
• Retrospective analysis of children diagnosed with Mycoplasma pneumoniae pneumonia.
• Assessment of neutrophil-to-lymphocyte ratio in conjunction with pulmonary consolidation.
• Evaluation of oxidative-antioxidant balance using bronchoalveolar lavage fluid (BALF).
• Children with pulmonary consolidation showed a significant oxidative-antioxidant imbalance.
• Higher neutrophil-to-lymphocyte ratios correlated with increased lipid peroxidation.
• Findings suggest a mediating role of the neutrophil-to-lymphocyte ratio in pulmonary responses.

Abstract