Maternal and personal smoking, genetic susceptibility, and risk of osteoarthritis: A population‐based prospective cohort study | Synapse
April 15, 2026
Maternal and personal smoking, genetic susceptibility, and risk of osteoarthritis: A population‐based prospective cohort study
Key Points
To evaluate the relationship between maternal and personal smoking and the risk of osteoarthritis (OA), taking genetic susceptibility into account.
Population-based prospective cohort design
Assessment of maternal and personal smoking habits
Analysis of genetic susceptibility factors
Evaluation of OA risk among participants
Both maternal and personal smoking are linked to higher OA risk
These associations hold true across varying genetic susceptibilities
No significant interaction between smoking and genetic factors in OA risk
Abstract
Both maternal and personal smoking are independently associated with an elevated risk of OA. These associations are universal across different genetic susceptibility of OA.