Diels-Alder Dimerization of Ene-Allenes and Enyne-Allenes Generated via the Propargylic Alder-Ene Reaction of Diynes and Triynes

Key Points

• The study aims to explore the Diels-Alder dimerization of ene-allenes and enyne-allenes derived from propargylic reactions.
• Conducted Diels-Alder dimerizations of synthesized ene-allenes and enyne-allenes.
• Utilized density functional theory (DFT) to investigate stereoselectivity and exo/endo modes.
• Analyzed the resulting spirocycles for functionalization and yield.
• Achieved successful dimerization of ene-allenes and enyne-allenes.
• Generated highly functionalized spirocycles.
• DFT studies indicated preferences for exo/endo configurations and stereoselectivity patterns.