LncRNA CASC15 serves as a diagnostic biomarker for postmenopausal osteoporotic fractures and its knockdown enhances HBMSC osteogenic differentiation via miR-152-3p

Key Points

• CASC15 serves as a diagnostic biomarker for osteoporotic fractures, linking it to postmenopausal bone health concerns.
• The key evidence highlights that knockdown of CASC15 significantly enhances the osteogenic differentiation of HBMSCs by involving miR-152-3p.
• Analysis indicates that using HBMSCs emphasizes the role of LncRNA in bone regeneration, positively affecting fracture healing.
• The findings may enable targeted strategies in osteoporotic fracture management, hence improving patient outcomes.