New pyrimidine derivatives as potential agents against hepatocellular carcinoma: design, synthesis, and in vitro and in vivo biological evaluations

Key Points

• This pyrimidine derivative may offer significant bioactivity against hepatocellular carcinoma.
• Notable biological evaluations revealed promising effects in both in vitro and in vivo models.
• Evaluation methods included extensive synthesis and testing across various biological assays.
• Future studies may validate these compounds' effectiveness in clinical applications.