Development of LMW chitosan-stabilized gold nanoparticle DNA biosensors functionalized with thiolated probe for Vibrio parahaemolyticus detection

Key Points

• Gold nanoparticle DNA biosensors effectively detect Vibrio parahaemolyticus in environmental samples, enhancing food safety.
• The detection limit for these biosensors reaches 10^5 CFU/mL, showcasing their sensitivity.
• Chitosan serves as a stabilizing agent, allowing for improved performance of the biosensors in various conditions.
• This approach may enable rapid and accurate detection of Vibrio parahaemolyticus in food matrices, potentially reducing public health risks.