M2 macrophage-derived exosomes mitigate acute inflammation following ischemic stroke

Key Points

• Exosomes from M2 macrophages significantly reduce acute inflammation after ischemic stroke, enhancing recovery.
• The novel anti-inflammatory pathway mediated by M2-exo shows promising therapeutic potential.
• Analysis demonstrates that M2 macrophage-derived exosomes target inflammatory processes effectively over time.
• The findings support further exploration of exosome-based treatments for ischemic stroke, indicating clinical relevance.