Computational physiological modeling for lung-specific ventilation and perfusion management in ex vivo lung perfusion

Key Points

• Improved understanding of lung physiology supports enhanced ex vivo lung perfusion management and safety.
• Key insights on ventilation and perfusion dynamics may reduce lung injury in extended-duration procedures.
• Computational physiological modeling assessed the dynamics of lung function during ex vivo lung perfusion.
• This work highlights the need for innovative management strategies in lung perfusion techniques.