Allogeneic Hematopoietic Cell Transplantation for Infantile Osteopetrosis: High Rates of Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease (SOS/VOD) and Transplant-Related Morbidity

Key Points

• High rates of sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) were observed post-transplant.
• Approximately 60% of infants experienced transplant-related morbidity after hematopoietic cell transplantation.
• Assessment included infants diagnosed with osteopetrosis and their post-transplant outcomes.
• This highlights the need for careful monitoring and management of complications during treatment.