Physiological role of gamma-glutamyl transpeptidase: Demise of the gamma-glutamyl cycle

Key Points

• Gamma-glutamyl transpeptidase plays a crucial role in cellular metabolism and detoxification processes, highlighting its importance.
• This study details the reduction of the gamma-glutamyl cycle, emphasizing oxidative stress impacts on enzymatic activities.
• Analyzing the functions of gamma-glutamyl transpeptidase reveals insights into its role in various physiological pathways over time.
• Elucidating these mechanisms may enable better understanding of metabolic disorders linked to mitochondrial dysfunction.