Depleting non-resolving neuroinflammation in chronic spinal cord injury attenuates thermal hypersensitivity

Key Points

• Thermal hypersensitivity decreases significantly following neuroinflammation depletion, implying a potential therapeutic route.
• Participants show a marked improvement with neuroinflammation-related interventions over a standard treatment period.
• Assessment utilizing molecular pathways focused on neuroinflammation allows for innovative treatment perspectives.
• Findings highlight the significance of targeting neuroinflammation for managing chronic pain conditions.