Risk Factors for Symptom Aggravation in Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion

Key Points

• To identify independent risk factors contributing to neurological deterioration in acute ischemic stroke due to large vessel occlusion.
• Observational analysis of stroke patients
• Assessment of homocysteine (Hcy) and LDL cholesterol (LDL-C) levels
• Measurement of onset-to-door time (ODT) and procedure duration
• Elevated Hcy levels significantly predict neurological deterioration
• High LDL-C levels are associated with increased risk of short-term worsening
• Prolonged ODT and procedure duration independently linked to neurological decline