This case demonstrates successful multimodal management of high-risk acetaminophen poisoning in an infant using extracorporeal toxin removal and adjunctive therapies. It highlights practical considerations for NAC dose adjustment during HD and CRRT and underscores important public health concerns regarding the accessibility and formulation of potentially lethal medications. Regulatory strategies limiting acetaminophen quantities per container and discouraging formulations attractive to young children may reduce the risk of severe exploratory ingestions.
Mero et al. (Wed,) studied this question.