Does achieving low CRP levels after statin therapy improve clinical outcomes compared to higher CRP levels in patients receiving statins?
Patients receiving statin therapy
Statin therapy with resultant low C-reactive protein (CRP) levels
Statin therapy with resultant higher C-reactive protein (CRP) levels
Clinical outcomes
Monitoring and targeting CRP levels, in addition to LDL cholesterol, may be important for optimizing cardiovascular risk reduction with statin therapy.
Patients who have low CRP levels after statin therapy have better clinical outcomes than those with higher CRP levels, regardless of the resultant level of LDL cholesterol. Strategies to lower cardiovascular risk with statins should include monitoring CRP as well as cholesterol.
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Ridker et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69dcca4a854f360ad635917b — DOI: https://doi.org/10.1056/nejmoa042378
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
Paul M. Ridker
Christopher P. Cannon
David A. Morrow
New England Journal of Medicine
Brigham and Women's Hospital
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