What question did this study set out to answer?

The aim is to evaluate the impact of CE-CT on SUV measurements in LAFOV-PET for lymphoma.

April 15, 2026Open Access

Contrast-enhanced CT for attenuation correction in ultra-high sensitivity long-axial field-of-view lymphoma PET: amplified quantification problems?

Key Points

The aim is to evaluate the impact of CE-CT on SUV measurements in LAFOV-PET for lymphoma.
Utilized CE-CT for attenuation correction in LAFOV-PET imaging.
Assessed SUV measurements in lymphoma lesions under ultra-high sensitivity mode.
Compared findings with conventional standard axial field-of-view PETs.
Observed higher SUV measurements in lymphoma lesions using CE-CT.
Noted increased quantification problems compared to standard axial PET.
Highlighted the need for careful interpretation of borderline cases.

Abstract

The use of CE-CT for AC of LAFOV-PET in UHS mode leads to higher SUV measurements. Also, lymphoma lesions show a consistent increase in uptake. The errors in the lesions seem higher than in conventional standard axial field-of-view PETs that use CE-CT for AC. Therefore, interpretation of borderline cases warrants attention to potential errors.

Bookmark

View Full Paper

Cite This Study

Penner et al. (Mon,) studied this question.

synapsesocial.com/papers/69df2c01e4eeef8a2a6b0ece https://doi.org/https://doi.org/10.1186/s40658-026-00866-4

Bookmark

View Full Paper