April 23, 2024Open Access

Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2– and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study

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Abstract

Datopotamab deruxtecan (Dato-DXd) is an antibody-drug conjugate consisting of a humanized antitrophoblast cell-surface antigen 2 (TROP2) monoclonal antibody linked to a potent, exatecan-derived topoisomerase I inhibitor payload via a plasma-stable, selectively cleavable linker.

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Cite this study

Bardia et al. (Tue,) studied this question.

www.synapsesocial.com/papers/68e6de6eb6db64358765a50e — DOI: https://doi.org/10.1200/jco.23.01909

Authors

Aditya Bardia

Ian E. Krop

Takahiro Kogawa

Journals

Journal of Clinical Oncology

Actions

Institutions

Harvard University

University of California, Los Angeles

Massachusetts General Hospital

References and Citations

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Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2– and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion