抄録 431: マリックエンザイム2阻害が示すセリン依存性トリプルネガティブ乳がんの代謝的脆弱性

Slayton ら (Fri,) はこの問題を研究しました。

www.synapsesocial.com/papers/68e72f48b6db6435876a8570 — DOI: https://doi.org/10.1158/1538-7445.am2024-431

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5. Abstract PS3-12-22: Tumor cell AADAT suppresses CD8+T cell function by depleting malate, driving progression in Triple-Negative Breast Cancer· 2026