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Ipilimumab, with or without a gp100 peptide vaccine, as compared with gp100 alone, improved overall survival in patients with previously treated metastatic melanoma. Adverse events can be severe, long-lasting, or both, but most are reversible with appropriate treatment. (Funded by Medarex and Bristol-Myers Squibb; ClinicalTrials.gov number, NCT00094653.)
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Hodi et al. (Sat,) studied this question.
www.synapsesocial.com/papers/6991393dd1ef3d049e6cff6c — DOI: https://doi.org/10.1056/nejmoa1003466
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
F. Stephen Hodi
Steven O’Day
David F. McDermott
New England Journal of Medicine
Harvard University
Washington University in St. Louis
Dana-Farber Cancer Institute
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