What is the prognostic significance of clinical and radiological haemorrhagic transformation subtypes on functional outcome and mortality in acute ischaemic stroke patients?
Acute ischaemic stroke (AIS) patients undergoing thrombolysis or thrombectomy
Clinical and radiological haemorrhagic transformation (HT) subtypes (sICH, PH, aICH, HI-2, HI-1)
Functional outcome, mortality, early neurological deterioration (END), or neurological complicationshard clinical
Different subtypes of haemorrhagic transformation in acute ischaemic stroke carry distinct prognostic implications, with parenchymal haematoma and symptomatic intracerebral haemorrhage driving mortality and worse functional outcomes.
Regardless of whether AIS patients undergo thrombolysis or thrombectomy, overall HT, sICH and PH (especially PH-2) are associated with a substantially increased risk of worse functional outcome, mortality, END or neurological complications. The presence of aICH is related to worse functional outcome but is independent of increased mortality. HI-2 impairs functional independence, and HI-1 does not cause neurological impairment.
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He et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69a3048aa60bae612d55e47f — DOI: https://doi.org/10.1111/ene.15482
Jinfeng He
Fangwang Fu
Wenyuan Zhang
European Journal of Neurology
Zhejiang University
Wenzhou Medical University
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
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