Substance use and menopausal hormone therapy: Treatment initiation and interruption among US women with and without HIV , 2008–2019

Key Points

• The rate of menopausal hormone therapy initiation was low, indicating potential barriers to access or acceptance for treatment.
• Moderate to severe vasomotor symptoms were reported among participants, indicating a need for effective management strategies.
• Patients with current tobacco use showed particularly high rates of treatment interruption, complicating hormone therapy management.
• Providers may need specific guidance to support individuals with substance use in accessing menopausal hormone therapy.