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Depression phenotypes informed by the RDoC framework using the Patient Health Questionnaire-9: A retrospective study in Peru | Synapse
March 3, 2026
Depression phenotypes informed by the RDoC framework using the Patient Health Questionnaire-9: A retrospective study in Peru
JF
Javier A. Flores-Cohaila
Universidad Científica del Sur
JH
Jeff Huarcaya-Victoria
Universidad Privada San Juan Bautista
CC
Cesar Copaja-Corzo
Universidad San Ignacio de Loyola
Key Points
Identifying depression phenotypes enhances understanding of mental health conditions across populations, especially in Peru.
The study reveals insights into varying depression types informed by the RDoC framework and assessed through the PHQ-9 scale.
Observational analysis leveraging data from the Patient Health Questionnaire-9 assesses depression characteristics retrospectively.
These findings suggest the need for tailored treatment strategies, emphasizing the importance of early identification based on phenotype.
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Flores-Cohaila et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75dcfc6e9836116a280fc
https://doi.org/https://doi.org/10.1016/j.sjpmh.2025.11.007