Fuzheng Shengbai decoction enhances antitumor immunity via YTHDC2-dependent stabilization of CLCA2 mRNA in colorectal cancer

Key Points

• Enhanced CD8+ T-cell activation indicates improved anti-colorectal cancer responses with FZSB treatment.
• A key mechanism involves the YTHDC2-CLCA2 axis through m6A-mediated mRNA stabilization.
• Fuzheng Shengbai decoction identifies a promising therapeutic avenue for colorectal cancer.
• Further research is required to validate these findings and explore clinical applications.